Disease: Myeloid neoplasm
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
YWHAE P62258 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Chaperone 0.98 0.530 0.692
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
PRR14L Q5THK1 proline rich 14 like 1.00 0.931 0.077
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
PAFAH1B1 P43034 platelet activating factor acetylhydrolase 1b regulatory subunit 1 1.00 0.504 0.769
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
JUN P05412 Jun proto-oncogene, AP-1 transcription factor subunit Transcription factor 6.0E-02 0.442 0.885
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
DDX41 Q9UJV9 DEAD-box helicase 41 5.6E-08 0.636 0.538